Figure 1

The Sim score between two CSs. It is presumed that a TR has 16 CAs and they are randomly distributed around the centroid (A). The TR is divided by four CSs (P₁, P₂, P₃ and P₄) defined by the indicated normal vectors and including the centroid. The S_i,jvalues of the CAs are shown in (B). If the TR is divided by two planes and the angle between the normal vectors is zero, i.e. P₁and P₁, the Sim score is Sim(P₁,P₁) = |-16/16| = 1. Similarly, if the angles between the vectors are π (i.e. P₁ and P₂), π/2 (i.e. P₁ and P₃) and π/4 (i.e. P₁ and P₄), the Sim scores are Sim(P₁,P₂) = |-16/16| = 1, Sim(P₁,P₃) = |0/16| = 0 and Sim(P₁,P₄) = |8/16| = 0.5, respectively.