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Table 2 Design of simulation 3 for evaluation

From: REMAS: a new regression model to identify alternative splicing events from exon array data

Gene ID

Treatment Group

Control Group

1

Exon 5~N (0, 1)

All exons ~N (1.5,1), correlated

 

Exon 6~N (0, 1)

 
 

Others ~N (2.5, 1), correlated

 

2

Exon 5~N (0, 1)

All exons ~N (2.5,1), correlated

 

Exon 6~N (0, 1)

 
 

Others ~N (1.5, 1), correlated

 

3

Exon 5~N (2.5, 1)

Exon 5~N (0, 1)

 

Exon 6~N (0, 1)

Exon 6~N (1.5, 1)

 

Others ~N (2.5, 1), correlated

Others ~N (1.5, 1), correlated

4

Exon 5~N (1.5, 1)

Exon 5~N (0, 1)

 

Exon 6~N (0, 1)

Exon 6~N (2.5, 1)

 

Others ~N (1.5, 1), correlated

Others ~N (2.5, 1), correlated

  1. The design of alternatively spliced exons is same with simulation 1, but the power of normal distribution is different between two sample groups to simulate the differential expression in gene level.