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Table 1 Correlation analyses for structural parameters, GC%, and RNAi activity

From: A structural interpretation of the effect of GC-content on efficiency of RNA interference

Pair of measures Pearson's correlation coefficient Significance of correlation
(p-value)
ΔGdisruption RNAi activity 0.2382 0.0165
siRNA GC% RNAi activity -0.1444 0.1497
siRNA MFE RNAi activity 0.0531 0.5982
Number of 3' free nts RNAi activity 0.0108 0.9146
Number of 5' free nts RNAi activity 0.0538 0.5933
Number of 3' free nts with ≥ 2 5' free nts RNAi activity 0.1311 0.2465
ΔGdisruption siRNA GC% -0.6832 3.519E-15