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Table 4 Chromosome-specific correlation and partial correlation. Chromosome-specific correlation and partial correlation between GC%, RR, and DT (negative log-transformed) using the 1 Mb window. A p-value for testing zero-correlation is included only when the correlation is not significant. n is the number of windows per chromosome (i.e., sample size). Acrocentric chromosomes are marked by *.

From: Partial correlation analysis indicates causal relationships between GC-content, exon density and recombination rate in the human genome

chr

GC%-RR

GC%-log(1/DT)

ρ (p-value)/partial-ρ (p-value)

RR-log(1/DT)

n

1

0.37/0.24

0.47/0.38

0.37/0.24

224

2

0.43/0.32

0.38/0.24

0.43/0.32

238

3

0.23/0.17(0.016)

0.17(0.015)/0.065(0.37)

0.51/0.49

194

4

0.51/0.34

0.52/0.37

0.48/0.29

187

5

0.58/0.43

0.56/0.40

0.47/0.21

175

6

0.29/0.40

0.51/0.21

0.65/0.50

166

7

0.20(0.01)/0.054(0.50)

0.34/0.28

0.47/0.43

154

8

0.41/0.17(0.048)

0.58/0.46

0.52/0.38

142

9

0.29/0.11(0.24)

0.39/0.30

0.51/0.45

114

10

0.37/0.21(0.015)

0.41/0.28

0.50/0.41

131

11

0.31/0.22(0.01)

0.23/0.063(0.48)

0.59/0.56

130

12

0.39/0.14(0.12)

0.51/0.37

0.58/0.48

129

13*

0.54/0.53

0.26/0.23(0.025)

0.13(0.20)/-0.012(0.91)

95

14*

0.36/0.41

0.67/0.69

0.086(0.42)/-0.23(0.035)

87

15*

-0.097(0.38)/-0.14(0.19)

0.19(0.096)/0.21(0.054)

0.22(0.04)/0.25(0.024)

82

16

0.18(0.11)/-0.14(0.22)

0.64/0.63

0.44/0.43

77

17

0.22(0.04)/0.012(0.92)

0.45/0.40

0.48/0.43

77

18

0.35/0.24(0.04)

0.27(0.02)/0.051(0.66)

0.67/0.63

74

19

0.45/0.18(0.18)

0.47/0.24(0.082)

0.71/0.63

54

20

0.089(0.50)/-0.13(0.31)

0.26(0.046)/0.28(0.033)

0.70/0.70

59

21*

0.13(0.48)/0.13(0.50)

0.92/0.92

0.088(0.61)/-0.079(0.67)

32

22*

0.32(0.06)/0.27(0.13)

0.40(0.02)/0.35(0.04)

0.21(0.22)/0.099(0.58)

34

ave

0.38/0.20

0.47/0.35

0.49/0.38

2655