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Figure 4 | BMC Bioinformatics

Figure 4

From: In silico saturation mutagenesis and docking screening for the analysis of protein-ligand interaction: the Endothelial Protein C Receptor case study

Figure 4

Key positions replaced in mutants with impaired ligand binding. Wild type EPCR residues are represented as colored spots corresponding to the Cα position. L69 (in green) was found substituted only in single mutants. Residues substituted in both single and double mutants are in yellow, while those observed in double mutants only are in red. PTY ligand is represented in sticks. Figure is drawn with Pymol (DeLano Scientific, San Carlos, CA, USA).

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