Figure 3
From: Modulation of p53 binding to MDM2: computational studies reveal important roles of Tyr100
(a),(b) Snapshots taken at the end of 10 ns simulation of Mo3A (See Table 1). MDM2 (green) has been shown in ribbon in 'a' and surface representations in 'b'; and p53 (red) has been shown in ribbon. The HB between residue pairs W23-L54, E28-Y100 and the polar interaction between the side chains of E28 and K51 have been shown with dashed (black) line in the picture 'a'. (c),(d) Snapshot taken at he end of Mc3A trajectory (See Table 1)