Figure 1

Mutation retrieval workflow. Workflow of mutation data retrieval with MutationTagger. A: PubMed IDs of abstracts mentioning proteins for given species are retrieved from a local database (gene2pubmed), which contains the results of our gene normalizing approach. Mutations are identified in the abstracts and stored (mutation2pubmed). The gene and mutation data is joined, filtered by sequence checks, and stored (mutation2gene). B: For a queried protein or gene relevant articles are retrieved from the Entrez database. Mutations are identified in the abstracts, sequence checks against the queried protein are performed, and the checked mutation data is exported to HTML or SQL.