Figure 4
From: Correlating protein function and stability through the analysis of single amino acid substitutions
SNAP performance for data not seen in training ( PMD07 ). SNAP predicted the effects of mutations that it has not encountered in training (PMD07, filled triangles) just as accurately (at default cutoff RI = 0; marked by X's) as the mutations in the larger PMD-foldx set (open triangles). This result suggests that effects of PMD-foldx mutants were not memorized in the course of SNAP training.