Extracting causal relations on HIV drug resistance from literature

BMC Bioinformatics

Table 7 Prediction results of mutation K65R and its related drugs.

Mutation	Drug	Resistance type	HIVDB	REGADB
K65R	3TC	I	I	I
K65R	ABC	I	I	S
K65R	AZT	S	S	S
K65R	D4T	I	I	S
K65R	DDI	I	I	I
K65R	FTC	I	I	I
K65R	TDF	I	I	R
K65R	DDC	I	N/A	N/A

The results of K65R mutation and its drug resistance value calculated by the system compared with the result of the Stanford HIVDB based on three levels of resistance: susceptible (S), intermediate resistant (I), and resistant (R). In addition, we also provided the output of the RegaDB to show the differences between the expert systems.

ISSN: 1471-2105