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Table 7 Prediction results of mutation K65R and its related drugs.

From: Extracting causal relations on HIV drug resistance from literature

Mutation

Drug

Resistance type

HIVDB

REGADB

K65R

3TC

I

I

I

K65R

ABC

I

I

S

K65R

AZT

S

S

S

K65R

D4T

I

I

S

K65R

DDI

I

I

I

K65R

FTC

I

I

I

K65R

TDF

I

I

R

K65R

DDC

I

N/A

N/A

  1. The results of K65R mutation and its drug resistance value calculated by the system compared with the result of the Stanford HIVDB based on three levels of resistance: susceptible (S), intermediate resistant (I), and resistant (R). In addition, we also provided the output of the RegaDB to show the differences between the expert systems.