EIF4E2 probesets are associated with breast cancer survival. Panel A. Schematic representation of EIF4E2 isoforms A and B, with region interrogated by probesets shown as Up (red arrow), and Down (blue arrow). For panels B, C, and D, the fraction of patients surviving in each cohort (vertical axis) is shown over time in years (horizontal axis) as a function of individual probeset expression or SplicerAV index. Survival of patients in the top (red line) and bottom (blue line) 50th percentile are plotted by individual probeset expression (B, C) and the SplicerAV index (D) within the Miller (left) and Pawitan (right) cohorts. Results of two-tailed logrank tests of survival are shown, with asterisks indicating significance at the .05 level.