Table 3 GO analysis of 241 genes predicted to undergo isoform changes between grade I and grade III breast tumors (GUYT).
From: SplicerAV: a tool for mining microarray expression data for changes in RNA processing
Molecular Function | # Genes | P-Value | Gene Symbols |
|---|---|---|---|
Guanyl-nucleotide exchange factor | 7 | 6.22E-03 | RAB3IP, RAPGEF2, GAPVD1, CD47, TRIO, ARHGEF7, AKAP13 |
Metalloprotease inhibitor | 2 | 6.52E-03 | TIMP2, TIMP3 |
Ubiquitin-protein ligase | 10 | 7.40E-03 | RNF130, TTC3 UBE3B, PML, TRIM26, RBCK1, MIB1, ZNF294, ZUBR1, TRIAD3 |
mRNA processing factor | 9 | 1.27E-02 | SYNCRIP, WDR33, SFRS8, SFRS15, TAF15, SF1, SF3B1, SFPQ, PRP6 |
Cytoskeletal protein | 4 | 3.42E-02 | DNAL1, NF2, KIF5C, DYNC1H1 |
Anion channel | 2 | 3.63E-02 | PML, CLCN3 |
G-protein modulator | 12 | 4.64E-02 | RAB3IP, RAPGEF2, GAPVD1, CD47, |
mRNA splicing factor | 6 | 4.94E-02 | TAF15, SFRS8, SF1, SF3B1, SFPQ, PRP6 |
Tyrosine protein kinase receptor | 4 | 4.97E-02 | TEK, TPR, IGF1R, PDGFRA |