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Table 3 Characterization of common de novo sequencing errors.

From: A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry

De novo sequencing error types Top sequence tags Consensus sequence tags
  Counts Percentage Counts Percentage
Substitution of a Q by GA 243 9.8% 174 14.6%
Substitution of an N by GG 51 2.1% 42 3.5%
Inversion of two adjacent residues 222 9.0% 103 8.7%
Subsitution of an end residue 1002 40.5% 421 35.4%
Subsitution of an internal residue 98 4.0% 59 5.0%
Other 861 25.8% 391 32.9%
Total 2477 100.0% 1190 100.0%