From: APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Method
Specificity
Recall
Precision
F1
ΔF1
Robetta
0.87
0.33
0.52
0.40
**
FOLDEF
0.88
0.26
0.48
0.34
-0.06
KFC
0.85
0.31
0.37
-0.03
MINERVA
0.90
0.44
0.65
+0.12
APIS (this work)
0.76
0.72
0.57
0.64
+0.24