From: Properties and identification of antibiotic drug targets
Feature | Non-targets | Bacterial targets | p-value comparing all targets to non-targets | E. coli targets | p-value comparing E. coli targets to non-targets |
---|---|---|---|---|---|
Length | 316 | 420 | 0.032 | 515 | 0.001 |
% Trp | 1.52 | 0.98 | 0.005 | 0.74 | 6 × 10-5 |
% Met | 2.95 | 2.54 | 0.099 | 2.26 | 0.015 |
% Val | 7.11 | 7.85 | 0.0002 | 7.94 | 0.017 |
% Pro | 4.67 | 5.52 | 0.007 | 5.45 | 0.042 |
% Leu | 10.63 | 8.91 | 4 × 10-6 | 9.36 | 0.046 |
% Gln | 3.92 | 3.43 | 0.049 | 3.19 | 0.078 |
% Gly | 7.1 | 7.70 | 0.099 | 7.75 | 0.12 |
% Glu | 5.83 | 6.46 | 0.32 | 6.41 | 0.22 |
% Lys | 4.31 | 4.33 | 0.40 | 4.54 | 0.29 |
% Arg | 5.58 | 5.31 | 0.58 | 6.51 | 0.33 |
% Asp | 5.05 | 5.89 | 0.008 | 5.39 | 0.38 |
% Thr | 5.35 | 5.80 | 0.074 | 5.58 | 0.38 |
% Cys | 1.3 | 0.96 | 0.01 | 1.07 | 0.39 |
% Tyr | 2.79 | 2.97 | 0.87 | 2.83 | 0.6 |
% His | 2.31 | 2.12 | 0.78 | 2.23 | 0.62 |
% Phe | 6.12 | 5.79 | 0.24 | 5.75 | 0.66 |
% Ala | 5.82 | 5.87 | 0.92 | 5.6 | 0.69 |
% Asn | 3.87 | 3.98 | 0.99 | 3.65 | 0.93 |
% Ser | 9.37 | 9.39 | 0.49 | 9.29 | 0.96 |
% Ile | 4.4 | 4.18 | 0.54 | 4.46 | 0.99 |
Hydrophobicity | -21 | -85 | 0.049 | -93 | 0.067 |
SignalP | 0.2 | * | * | 0.2 | 0.83 |
NetNGlyc | 1.1 | 1.3 | 0.52 | 1.1 | 0.75 |
NetOGlyc-S | 0.1 | 0.00 | 0.57 | 0 | 0.29 |
NetOGlyc-T | 0.6 | 0.7 | 0.15 | 0.5 | 0.97 |
LCR | 0.9 | 0.9 | 0.80 | 0.9 | 0.84 |
% α-Helix | 42 | 32 | 3 × 10-4 | 32 | 0.015 |
% β-Sheet | 15 | 21 | 1.5 × 10-4 | 22 | 0.002 |
THMM | 1.4 | 0.3 | 0.023 | 0.5 | 0.009 |
pI | 7.1 | 7.0 | 0.67 | 6.9 | 0.4 |