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Figure 6 | BMC Bioinformatics

Figure 6

From: TumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays

Figure 6

ROC evaluation (Chr 10). (a) Left panels: The region 80.0-109.0 Mb on Chr 10 in tumor-normal sample TCGA-23-1027 has a change point at approximately 94.0 Mb, which separates a normal diploid state from a deletion. 1,276 loci in each of these two states are used for the evaluation. All 53 loci in the safety region have been excluded. (b) Right panels: The region 106.5-113.5 Mb on Chr 10 in tumor-normal sample TCGA-23-1027 has a change point at approximately 110.0 Mb, which separates a copy-neutral LOH region from a deletion. 254 loci in each of these two states are used for the evaluation. All 59 loci in the safety region have been excluded. The outline is the same as in Figure 5.

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