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Figure 7 | BMC Bioinformatics

Figure 7

From: Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data

Figure 7

Characterizing the temporal parameters of origins firing/replication. (A) Distributions of origin firing efficiency in S.cerevisiae and S.pombe. (B) Correlation between firing efficiency and other parameters: T s (firing starting time), T e (firing ending time), T se (average firing time), T0 (replication initiation time), T100 (replication completion time), T50 (average replication time) and DT (replication span). (up) Correlation obtained from two DNA replication microarray data sets of S.cerevisiae: Cer-Raghuraman and Cer-Alvino; (bottom) Correlation obtained from microarray data sets of S.pombe: Pom-Heichinger and Pom-Eshaghi-Repeat1/2. (C) Correlation between origin firing efficiency and the factors that may regulate efficiency: strength of ACS motif, Histone occupancy level and AT richness around origins.

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