Table 1 64 mRNA triplets and associated inhibition parameters, P.
From: Antisense DNA parameters derived from next-nearest-neighbor analysis of experimental data
NNN triplet or other parameter (5' to 3' in mRNA) | Values of antisense inhibition parameter P (%) from fit to 112 sequences ± standard error from SVD analysis | Number of NNN triplet or other parameter in data set |
|---|---|---|
AAA | 2.98 ± 2.08 | 30 |
AAC | 5.96 ± 1.45 | 32 |
AAG | 0.48 ± 1.82 | 36 |
AAU | -3.52 ± 1.76 | 30 |
ACA | -3.78 ± 1.67 | 48 |
ACC | 4.63 ± 2.79 | 25 |
ACG | 1.82 ± 1.69 | 28 |
ACU | 3.81 ± 1.66 | 33 |
AGA | 3.23 ± 1.99 | 40 |
AGC | 3.86 ± 1.46 | 39 |
AGG | 4.83 ± 1.82 | 52 |
AGU | -4.72 ± 2.20 | 17 |
AUA | 0.29 ± 2.42 | 15 |
AUC | 3.27 ± 2.07 | 19 |
AUG | 0.45 ± 1.63 | 67 |
AUU | 1.05 ± 1.97 | 21 |
CAA | 1.83 ± 1.65 | 37 |
CAC | -1.51 ± 1.31 | 46 |
CAG | -1.47 ± 1.49 | 38 |
CAU | 5.77 ± 1.62 | 29 |
CCA | -0.99 ± 2.14 | 26 |
CCC | -3.73 ± 2.06 | 30 |
CCG | 3.09 ± 1.28 | 58 |
CCU | 5.48 ± 1.76 | 35 |
CGA | 5.43 ± 1.64 | 40 |
CGC | 7.38 ± 1.32 | 33 |
CGG | 5.65 ± 1.49 | 51 |
CGU | -5.02 ± 1.96 | 19 |
CUA | 13.27 ± 2.79 | 14 |
CUC | 1.37 ± 1.75 | 31 |
CUG | 0.87 ± 1.75 | 44 |
CUU | -4.62 ± 1.64 | 28 |
GAA | 3.57 ± 2.00 | 53 |
GAC | 1.08 ± 1.67 | 37 |
GAG | -2.19 ± 1.07 | 63 |
GAU | 4.87 ± 1.71 | 47 |
GCA | 6.89 ± 1.64 | 46 |
GCC | -1.26 ± 1.57 | 58 |
GCG | 3.96 ± 1.59 | 41 |
GCU | 6.20 ± 1.91 | 31 |
GGA | 2.96 ± 1.10 | 82 |
GGC | -2.70 ± 1.10 | 56 |
GGG | 2.06 ± 1.28 | 76 |
GGU | 8.28 ± 1.99 | 30 |
GUA | -8.59 ± 2.99 | 15 |
GUC | 1.85 ± 1.84 | 24 |
GUG | -3.40 ± 1.46 | 42 |
GUU | 10.43 ± 2.95 | 18 |
UAA | -2.48 ± 3.44 | 8 |
UAC | 0.94 ± 1.91 | 19 |
UAG | 10.37 ± 2.55 | 11 |
UAU | -2.06 ± 2.69 | 16 |
UCA | 2.50 ± 1.75 | 30 |
UCC | 4.20 ± 1.98 | 36 |
UCG | 4.57 ± 2.47 | 16 |
UCU | -4.60 ± 2.60 | 18 |
UGA | -4.28 ± 1.93 | 38 |
UGC | 7.26 ± 1.14 | 48 |
UGG | -1.93 ± 1.33 | 65 |
UGU | 1.75 ± 2.00 | 33 |
UUA | 1.80 ± 3.21 | 10 |
UUC | 0.19 ± 2.06 | 26 |
UUG | 4.88 ± 2.28 | 31 |
UUU | 0.81 ± 2.59 | 25 |
A549 cell | 10.59 ± 1.78 | 62 |
CRAF1 | 3.65 ± 2.33 | 52 |
BCL2 | -3.10 ± 1.85 | 29 |
AKT2 | 8.97 ± 4.43 | 7 |
PKC-α | -3.75 ± 2.76 | 24 |