Cnstream: Sensitivity gain. Intensity plots of several probes of those loci where CNstream made more calls than PennCNV (Table 2). Samples called as deletions are plotted in red and those with amplifications in blue. As shown, the intensity measurements of these samples match a typical CNV pattern. However, several loci match the CNV pattern but are assigned to the normal state. This is because these particular samples do not show consistent behaviour throughout the adjacent probes that are analyzed by CNstream.