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Figure 6 | BMC Bioinformatics

Figure 6

From: Machine learning approach to predict protein phosphorylation sites by incorporating evolutionary information

Figure 6

Fragment of the PSSM Profile of the protein P12023 to form a training instance for the SVMs. The fragment of this PSSM Profile of the protein P12023 includes position specific scores from position 191 to 205. Here, serine at position 198 is non-phosphorylated (according to the rule of negative annotations in our study) and hence the linear arrangement of the scores 5 positions upstream and 5 positions downstream from the position 198 form a negative instance of window size 11. A negative instance of serine residue was prepared by choosing a window over the non-phosphorylated serine of size 11 and convert the 11 × 20 matrix into a 220 size single dimensional linear array of scores which will eventually represent a negative instance for the SVMs-training.

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