Skip to main content

Table 1 Motif enrichment analysis.

From: HAT: Hypergeometric Analysis of Tiling-arrays with application to promoter-GeneChip data

  MAT HAT
Nr Motif Hits Fold- change p -value Motif Hits Fold- change p -value
1 AP2alpha 9735 1.606 0.0 M00117.CEBPbeta 1532 2.325 2.837E-185
2 Elk-1 5380 1.707 9.226E-286 M00770.CEBP 3076 1.766 2.229E-183
3 M00470.AP-2 gamma 5938 1.641 1.823E-274 M00912.C-EBP 3036 1.715 1.309E-164
4 M00109.CEBPbeta 6170 1.617 3.519E-269 cEBP 1928 1.965 1.886E-157
5 M00695.ETF 3449 1.885 3.049E-250 M00116.CEBPalpha 2689 1.722 4.296E-148
6 M00025.Elk-1 2979 1.949 1.763E-237 M00109.CEBPbeta 1278 2.161 2.349E-132
7 M00446.Spz1 4863 1.665 3.901E-237 M00190.CEBP 2402 1.719 9.670E-132
8 M00008.Sp1 5135 1.625 1.038E-228 M00098.Pax-2 1799 1.578 8.565E-73
9 E74A 3635 1.691 7.076E-188 M00496.STAT1 1909 1.545 8.877E-71
10 M00771.ETS 3756 1.674 2.374E-187 M00971.Ets 1917 1.508 4.418E-64
  1. The top 10 motifs enriched in the detected regions-of-interest (α = 1 × 10-5) by HAT and MAT for the cebpa-study (ChIP-on-chip). Among the top 10 motifs enriched in the regions-of-interest detected with HAT, seven contained the CEBP binding motif whereas for MAT, only one contained the CEBP binding motif. For each reported motif, the number of hits within the regions-of-interest are counted, their fold change computed, and the p-value derived using the binomial test.