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Table 5 Brief description and comments on some genes (of datset-1) found to be differentially expressed and associated with RhoG from literature.

From: Bayesian integrated modeling of expression data: a case study on RhoG

Gene Comment Fold change(natural scale) Pubmed Id (PMID) Posterior probabilities
ARHGEF3 ARHGEF3 form complex with G proteins and stimulate Rho-dependent signals. 2.2 12221096 p+ = 1
ICAM1 ICAM1 binds to integrins of type CD11a/CD18, or CD11b/CD18 and stimulates intercellular signaling. 1.6 17875742 p+ = 0.9913
IL6 IL6 is an immunoregulatory cytokine that activates a cell surface signaling assembly composed of IL6, IL6RA, and the shared signaling receptor gp130. 4.2 15578470 p+ = 1
JUN This gene encodes a protein which interacts directly with specific target DNA sequences to regulate gene expression. 1.8 12739001, 1620121, 9671479, 10744696 p+ = 0.9935
NFKB1 NFKB is a transcription regulator that is activated by various intra-and extra-cellular stimuli. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. 1.9 12670394, 11803464, 12376551 p+ = 0.9942
NISCH NISCH is involved in the regulation of cell migration and cell invasion. 1.9 12890925 p+ = 0.9965
PCNA PCNA is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein helps increase the processivity of leading strand synthesis during DNA replication. 0.76 12167123 p- = 1
PTGS2 Prostaglandin-endoperoxide synthase is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. 2.3 10974444 p+ = 1
RHOF RHOF functions cooperatively with CDC42 and Rac to generate filopodia increasing the diversity of actin-based morphology. 3.7 15894457 p+ = 0.9994