Figure 1
From: An integrated Bayesian analysis of LOH and copy number data
Scheme of Model 1. The vector X of the homozygous status of all SNPs in abnormal cells is completely determined, given the vector XNof their homozygous status in normal cells and the vector 
of their corresponding copy number events. Using this relationship among X, XNand , we can estimate , given the observations Ycnand Y (respectively, the raw log2ratio of the copy number and the homozygous status in abnormal cells detected by the genotype calling algorithm) and by specifying the prior distribution of XN. The observations Ycnare used to defined the prior distribution of in the Bayesian model.