Figure 6

Technical noise in the MAQC dataset: (a) - (c) show the empirical pdf of the difference between two technical repeats in blue and the fitted normal pdf in red, for (a) all ranges of intensities, (b) 6.75 <I < 7.25, (c) 8.75 <I < 9.25. The p-value of the Kolmogorov-Smirnov test for normality is indicated in each figure. (d)-(f) Scatter plots of the square root of the variance estimator vs. the mean intensity, and its properties for different number of repeats; the black line indicates the estimated variance using our approach. (g) and (h) show the average and standard deviation lines from (d)-(f) (data used: GSE5350).