Figure 6
From: Applying unmixing to gene expression data for tumor phylogeny inference
Phylogenies inferred on components derived from Jones et al. [33]. Each phylogeny shows nodes labeled with component numbers. We further manually added labels reflecting approximately which tumor types are most specifically labeled by a given component based on Tables 1 and 2: NOR (normal cells); LCC/AD (large cell carcinoma and adenocarcinoma); SCC (small cell); CA (carcinoid); CMB (combined small cell/adenocarcinoma) and NOR/SCC (normal and small cell). Edges with over 50% confidence are shown as solid lines while those between 10% and 50% confidence are shown as dashed lines. Edges with confidence below 10% are omitted. Edges are labeled by confidences rounded to the nearest percent. (a) Phylogeny derived from four mixture components. (b) Phylogeny derived from six mixture components.