Applying unmixing to gene expression data for tumor phylogeny inference

BMC Bioinformatics

Table 2 Mixture fractions averaged by tumor type for a six component inference.

	Comp. 1	Comp. 2	Comp. 3	Comp. 4	Comp. 5	Comp. 6
Normal	0.4017	0.1134	0.0993	0.0563	0.2338	0.0955
Adenocarcinoma	0.2625	0.1748	0.0960	0.0627	0.2556	0.1483
Small cell (cell lines)	0.1585	0.0705	0.2818	0.0645	0.3151	0.1095
Small cell (primary)	0.2539	0.0677	0.1913	0.0301	0.3252	0.1317
Carcinoid	0.1670	0.0674	0.1681	0.2868	0.2358	0.0747
Large cell neuroendocrine	0.2591	0.1206	0.1955	0.0434	0.2977	0.0838
Large cell carcinoma	0.2461	0.2110	0.1264	0.0257	0.2852	0.1056
Combined SCLC/AD	0.1270	0.2000	0.1425	0.0695	0.0938	0.3672

Columns correspond to mixture components from a six-component inference. Rows correspond to distinct tumor types, as annotated by Jones et al. [[33]].

ISSN: 1471-2105