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Table 3 TPR and FPR at significance of 0.05

From: Parallel multiplicity and error discovery rate (EDR) in microarray experiments

   

Methods

   
 

EDR

Bonf

BH

BY

qvalue

rawp

DEGs

1070

606

1420

974

1734

1833

TP

90

63

101

83

106

109

FP

980

543

1319

891

1628

1724

TN

3774

4238

3424

3870

3110

3011

FN

91

118

80

98

75

72

TPR

0.4972

0.3481

0.5580

0.4586

0.5856

0.6022

FPR

0.2061

0.1136

0.2781

0.1871

0.3436

0.3641

  1. The expression data set was downloaded from http://www.ambystoma.org and was preprocessed by the RMA method [38]. Differentially expressed genes (DEGs) were detected at the significance level of 0.05 by the EDR method and the other methods from the multtest package [39]. The resultant DEGs were compared with the true DEGs (TP) measured by digital expression. False positives (FP) are those DEGs that are not found to be differential in digital expression analysis. True negatives (TN) are those genes that are not differential in both platforms.