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Figure 6 | BMC Bioinformatics

Figure 6

From: Investigating the validity of current network analysis on static conglomerate networks by protein network stratification

Figure 6

Functional enrichment in the total network and stratified tissue-specific subnetworks using GO annotations for proteins. Functional classification of proteins in each of the level-3 stratified tissue-specific subnetworks is evaluated using GO biological process terms. GO functional enrichment is assessed by Fisher's exact tests, and highly enriched terms with p-value < 5e-4 are shown in the figure. (Left) Different colors indicate significance of pairwise functional enrichment differences between proteins in the two networks/subnetworks, using GO slim high level terms. (Top right) Different colors indicate significance of differences in the distribution of each GO slim function term by protein annotations among networks.

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