Table 2 The optimal site feature set

1

6mer seed match

11

Number of matches in total region

2

Conservation score of 3' context region

12

Binding energy of seed region

3

Number of matches in seed region

13

Seed conservation score

4

7mer_A1 seed match

14

p7 match status

5

7mer_m8 seed match

15

Context nt type of r1

6

7mer_m1 seed match

16

Binding energy of total region

7

8mer_A1 seed match

17

conservation score of 5' context region

8

Accessibility energy

18

Number of mismatches in seed region

9

8mer_m1 seed match

19

p5 match status

10

6^th 2mer status

20

p2 match status

21

p12 match status