Table 2 Top Predicted Reactions for 4 drugs.
Drug Name | Reaction Name | Sub System | Target Enzyme | Score |
|---|---|---|---|---|
Cladribine | Glutathione peridoxase | Glutathione Metabolism | GPX1/GPX2/GPX4 | 0.6145 |
Daunorubicin | Glutathione peridoxase | Glutathione Metabolism | GPX1/GPX2/GPX4 | 0.5631 |
Azathioprine/Mercaptopurine | Gamma-glutamyl hydrolase (5DHF), lysosomal | Folate Metabolism | GGH | 0.5692 |
| Â | Ornithine mitochondrial transport via proton antiport | Transport, Mitochondrial | SLC25A15/SLC25A2 | 0.5598 |
| Â | 5'-nucleotidase (GMP) | Nucleotides | NT5C2 | 0.5477 |
| Â | Folylpolyglutamate synthetase (DHF) | Folate Metabolism | FPGS | 0.545 |