|
PPI Network
|
#Proteins
|
#Interactions
|
Avg node deg
|
#Derived MCL
|
complexes (Recall) MCL-CAw
|
|---|
|
Consol3.19
|
1622
|
9704
|
11.96
|
79 (0.545)
|
82 (0.566)
|
|
Consol0.623
|
5423
|
102393
|
37.76
|
74 (0.321)
|
84 (0.375)
|
|
ICD(Cons3.19)
|
1161
|
8688
|
14.96
|
58 (0.408)
|
63 (0.443)
|
|
ICD(Cons0.623)
|
1273
|
19996
|
31.41
|
52 (0.353)
|
56 (0.381)
|
|
FSW(Cons3.19)
|
1123
|
8694
|
15.48
|
59 (0.401)
|
65 (0.442)
|
|
FSW(Cons0.623)
|
1341
|
20696
|
30.87
|
54 (0.360)
|
57 (0.380)
|
- The Consolidated3.19 and Consolidated0.623 networks were subsets of the Consolidated network [11] derived with PE cut-offs 3.19 and 0.623, respectively. We ran ICD and FSW schemes on these networks. Consolidated0.623 had significant amount of false positives (about 81%) that were discarded by the scoring. The performance of MCL-CAw was only marginally better than MCL on Consolidated3.19, but MCL-CAw performed considerably better than MCL on the "more noisy" Consolidated0.623.
