Table 5 The significant amino acid pairs that surround the O-linked glycosylated serine and threonine on transmembrane (TM) proteins and non-transmembrane (non-TM) proteins that are extracted from release 15.0 of UniProt.

TM proteins

non-TM proteins

TM proteins

non-TM proteins

Pair

F-score

Pair

F-score

Pair

F-score

Pair

F-score

(+3T, +9E or +9T)

0.071

(+1G,-2E)

0.058

(+5 S,-9 M or -9P)

0.057

(+3P,-1P')

0.078

(-7T,+2 S or +3S)

0.064

(+1G,-1G)

0.041

(+5 S,-7T or -7S)

0.053

(+1P,-1P')

0.058

(+5P,+3P or +3T)

0.064

(+1G,+11G)

0.041

(+5P,+9E or +9P)

0.05

(+3P,+1P')

0.053

(+1T,+4P)

0.056

(+1G,+5G)

0.04

(-7T,-6 S or -6T)

0.049

(-1P,+5P')

0.053

(+1P,-1P)

0.056

(+1G,-3G)

0.034

(+5E,+1P or +1T or +1V)

0.047

(-4T,+3P')

0.036

(-7P,-5T)

0.053

(+1G,+10S)

0.034

(+7T,+8 S or +8P)

0.047

(+1P,+5P')

0.033

(+1G,+8E)

0.049

(+4 S,+5G)

0.032

(-7T,+8T)

0.044

(-4T,-1P')

0.033

(-7T,-12A or -12S)

0.047

(-1G,-2E)

0.031

(+7T,+10P or +10S)

0.043

(-4T,+14T')

0.033

(-7T,+6T)

0.047

(-5 S,+12S)

0.029

(-7T,-12S)

0.042

(-4T,+4T')

0.032

(+1G,-13D)

0.046

(-1P,-3P)

0.028

(+5P,-9T or -9V)

0.042

(+3T,+2A')

0.031

(+5P,-12S)

0.046

(+4 S,+1G)

0.027

(+1 S,-8 S or -8T)

0.041

(-4T,-10T')

0.030

(-7P,-10 S or -10T)

0.045

(+1G,+2E)

0.027

(+1T,+11 S or +11P)

0.041

(-4T,+2T')

0.030

(+3P,+11S)

0.043

(-5 S,+9A)

0.027

(+7P,+12 S or +12T)

0.040

(-1A,+3P')

0.030

(-7G,+6K or +6H)

0.038

(+9A,-5S)

0.027

(-7 S,+10S)

0.039

(+3T,+10I)

0.036

(+1T,-7T)

0.026

(+7 S,+10S)

0.039

(+1G,-1G)

0.034

(+4P,-3P)

0.025

(+1P,-13Q or -13T)

0.037

(-1G,-3G)

0.025

(-7P,-11 S or -11L)

0.036

(-1P,+3P)

0.025

(+1P,-3P or -3S)

0.036

(-5G,-4D)

0.025

(+5T,+10 S or +10E)

0.036

(-5 S,+2S)

0.024

(+5E,-7 S or -7T)

0.036

(+9A,+12S)

0.024

(+7P,+6D)

0.035

(-5 S,-12T)

0.023

(+1 S,-6 S or -6T)

0.034

(-1G,+9G)

0.021

(-7 S,-13P)

0.033

(-5 S,-7S)

0.019

(+1T,-13L or -13D)

0.030

(-1G,+7S)

0.018

(-10P,+7P or +7E)

0.017

(+4 S,+7S)

0.017

(+4 S,+12S)

0.017

(+4 S,-2E)

0.017

(-1G,+4S)

0.017

(-5G,-6S)

0.017

(+4 S,+14S)

0.016

(-5G,+10S)

0.015