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Table 3 Estimated values of the D-optimal criterion for different replications and perturbations.

From: Thermodynamically consistent Bayesian analysis of closed biochemical reaction systems

Perturbation

D

NO: 1 replication

-3.0123

NO: 2 replications

-3.4950

NO: 3 replications

-3.7544

YES: Shc*

-3.1398

YES: Grb2

-3.0747

YES: Sos

-3.4531

YES: Shc*, Grb2

-3.9279

YES: Shc*, Sos

-3.7716

YES: Grb2, Sos

-3.6363

YES: Shc*, Grb2, Sos

-4.1039

  1. The measurement errors are i.i.d. zero-mean Gaussian with standard deviation σ = 0.3.
  2. Logarithmic sampling is used with Q = 6.