Figure 1

BIANA Architecture. BIANA is composed of 4 different modules: Database Module, Parser Module, Network Module and Session Management Module. Database Module handles communication between BIANA and MySQL database. Parser Module imports data into BIANA database. Network Module performs all network procedures using NetworkX package. Session Management Module to handle biological data sets and networks. BIANA Cytoscape Plugin is a separate interface that communicates Cytoscape with BIANA through a socket. BIANA framework can be executed with Python interpreter (as well as command line python scripts) or in Cytoscape with a plugin.