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Table 3 Improvement in F1 score for H. sapiens PPI dataset

From: An improved method for scoring protein-protein interactions using semantic similarity within the gene ontology

Best-match average

Maximun

 

IEA-

  

IEA+

  

IEA-

  

IEA+

 

CC

BP

MF

CC

BP

MF

CC

BP

MF

CC

BP

MF

3.44

1.51

2.42

1.28

1.64

4.0

2.7

1.48

2.0

1.53

1.58

1.50

  1. Average improvement in F1 scores achieved by TCSS over Resnik for best-match average and maximum approaches. TCSS does 2.2 times better than Resnik for cellular component (CC), 1.5 times for biological process (BP), and 2.5 times for molecular function (MF) ontologies on average.
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BMC Bioinformatics

ISSN: 1471-2105

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