Figure 2
From: Systematic integration of experimental data and models in systems biology
Schematic view of the data transformations enacted by the systems biology workflows. (A and B) The modelling workflow generates the qualitative network structure of a metabolic pathway to which parameters in the form of reaction kinetics and starting concentrations (grey) are added by the parameterisation workflow. (C and D) The calibration workflow tunes the parameters in the model based on experimental data; the model is then ready for predictive studies by the simulation workflow, whose results are returned in SBRML format.