Figure 3
From: PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Top three significant Apc petals. The top three petals, Apc-Hapln1 (left, p = 0.0068), Apc-Kras (middle, p = 0.0157), and Apc-Prkd1 (right, p = 0.0167), found to be significant after coexpression correlation with proteomic targets are shown. The darker nodes represent CAN-gene proteins. When searching for paths, CAN-genes were not differentiated from other proteins on the network, hence multiple CAN-genes exist in some of the petals. The dashed edges represent novel interactions predicted to exist on the network, whereas solid edges are known interactions.