Table 5 Comparison of the composition of the amino acids in hyperthermophilic and mesophilic proteins and their significance p-values of t-test and paired t-test.
Amino acid | Composition in HP | Composition in MP | p-value (t-test) | p-value (paired t-test) |
|---|---|---|---|---|
S | 0.044 ± 0.016 | 0.050 ± 0.015 | 9.60×10-9 | 5.61×10-12 |
Q | 0.019 ± 0.011 | 0.037 ± 0.015 | 6.81×10-85 | 1.24×10-94 |
N | 0.035 ± 0.014 | 0.035 ± 0.015 | 0.88 | 0.85 |
T | 0.042 ± 0.014 | 0.055 ± 0.016 | 1.02×10-40 | 2.44×10-56 |
C | 0.009 ± 0.011 | 0.010 ± 0.011 | 0.36 | 0.08 |
G | 0.075 ± 0.019 | 0.079 ± 0.020 | 9.14×10-4 | 9.68×10-10 |
A | 0.066 ± 0.023 | 0.080 ± 0.028 | 3.41×10-48 | 1.08×10-87 |
H | 0.017 ± 0.010 | 0.024 ± 0.013 | 3.00×10-20 | 4.64×10-40 |
M | 0.024 ± 0.011 | 0.026 ± 0.010 | 0.02 | 3.00×10-3 |
Y | 0.033 ± 0.014 | 0.027 ± 0.013 | 6.10×10-15 | 4.47×10-31 |
F | 0.038 ± 0.015 | 0.033 ± 0.014 | 3.00×10-8 | 1.29×10-14 |
V | 0.086 ± 0.021 | 0.082 ± 0.020 | 2.32×10-4 | 5.36×10-7 |
L | 0.089 ± 0.021 | 0.089 ± 0.022 | 0.73 | 0.59 |
P | 0.041 ± 0.015 | 0.040 ± 0.014 | 0.39 | 0.16 |
I | 0.077 ± 0.020 | 0.066 ± 0.019 | 6.46×10-20 | 3.15×10-29 |
W | 0.008 ± 0.007 | 0.007 ± 0.007 | 0.05 | 3.00×10-3 |
D | 0.050 ± 0.015 | 0.057 ± 0.016 | 1.92×10-12 | 5.64×10-22 |
E | 0.097 ± 0.023 | 0.079 ± 0.022 | 6.73×10-38 | 5.63×10-75 |
K | 0.091 ± 0.023 | 0.060 ± 0.023 | 1.21×10-87 | 5.25×10-117 |
R | 0.056 ± 0.023 | 0.055 ± 0.023 | 0.57 | 0.36 |