Table 2 Summary of mutations exclusive to amyloid formers
From: Using simple artificial intelligence methods for predicting amyloidogenesis in antibodies
Exposure, Region | Increased β-sheet- forming propensity | Decreased β-sheet- forming propensity |
|---|---|---|
Exposed CDR | 20 | 9 |
Exposed FR | 20 | 19 |
Buried CDR | 21 | 16 |
Buried FR | 12 | 21 |