Table 4 Some significant SNPs identified by our method on WTCCC RA data. These SNPs covers the regions which are moderate associated with RA as reported in [1].
SNPs | Location | Related Genes | P-value |
|---|---|---|---|
rs7539166 | 1p36 | TMEM51 | < 10-30 |
rs384843 | 1p36 | NBPF3 | 5.2 × 10-9 |
rs7516721 | 1p36 | GPR3 | 7.7 × 10-14 |
rs4959053 | 6p21 | PSORS1C1 | < 10-30 |
rs6457617 | 6p21 | MHC region | 1.3 × 10-15 |
rs6973565 | 7q32 | PLXNA4 | 1.2 × 10-9 |
rs10250029 | 7q32 | CHCHD3 | < 10-30 |
rs10751815 | 10p15 | ADARB2 | < 10-30 |
rs4266996 | 10p15 | unknown | < 10-30 |
rs17147777 | 10p15 | unknown | < 10-30 |
rs8129909 | 21q22 | IGSF5 | < 10-30 |
rs16999716 | 21q22 | DSCAM | 9.2 × 10-9 |
rs4542939 | 21q22 | DSCAM | 8.3 × 10-9 |
rs13047947 | 21q22 | PDE9A | < 10-30 |
rs140344 | 22q12 | unkown | < 10-30 |
rs5749509 | 22q12 | SYN3 | < 10-30 |
rs6518796 | 22q12 | SYN3 | < 10-30 |