Table 1 Penetrance sets and their effects. G: genotype, d: normal allele/haplotype, D: disease allele/haplotype, A: affected.
From: A novel approach for haplotype-based association analysis using family data
Penetrance Set | Values | λ 1 | λ 2 | Pr(G= dd|A) | Pr(G= dD|A) | Pr(G= DD|A) |
|---|---|---|---|---|---|---|
A | (0.05, 0.15, 0.25) | 3 | 5 | 0.579 | 0.386 | 0.036 |
B | (0.01, 0.1, 0.15) | 10 | 15 | 0.293 | 0.652 | 0.054 |
C | (0.05, 0.3, 0.5) | 6 | 10 | 0.407 | 0.543 | 0.050 |