Figure 1
From: Comparative analysis of thermophilic and mesophilic proteins using Protein Energy Networks
Transition profile of largest connected component in Adenylate Kinases. Largest Connected Component (LCC) profile of thermophile(1zip, also orange cartoon) and mesophile(1ak2, also cyan cartoon) Adenylate Kinases is shown in the figure. The thermophile has a larger LCC (shown as red VdW representation over the cartoon representation of the protein) than the mesophile (shown as blue VdW spheres). The LCC represented in VdW spheres are for PEN-14. The region below the transition is the low energy region (yellow) where LJ interactions dominate. The high-energy region (green) beyond ~-25 KJ/mol is dominated mainly be salt-bridge interactions. The region of transition is in between these low and high energy regions.