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Figure 1 | BMC Bioinformatics

Figure 1

From: An automated framework for understanding structural variations in the binding grooves of MHC class II molecules

Figure 1

Structure of an MHC class II binding groove. (A) Binding domain of HLA-DR1 [PDB:1DLH], with the five pockets in the binding groove highlighted (P1 - red; P4 - yellow; P6 - green; P7 - blue; P9 - purple). Lines are drawn between the centres of binding site atoms that can be touched simultaneously by a probe sphere. (B) The influenza virus peptide from [PDB:1DLH] is shown above the binding groove, with peptide side chains shown in the same colour as the pockets into which they fit.

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BMC Bioinformatics

ISSN: 1471-2105

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