Figure 1
From: Analysis and verification of the HMGB1 signaling pathway
Schematic view of HMGB1 signal transduction. Blue nodes represent tumor suppressor proteins; red nodes represent oncoproteins/lipids; brown node represents protein complex formed by oncoprotein E2F and tumor suppressor protein RB. Solid lines with arrows denote protein transcription, degradation or changes of molecular species; dashed lines with arrows denote activation processes.