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Table 4 Verification of property 4 and 5

From: Analysis and verification of the HMGB1 signaling pathway

Property 4: Pr≥ 0.9[F600(CyclinE> 900)]

Property 5: Pr≥ 0.9[F600(CyclinD> 900)]

HMGB1

# of Samples

# of Success

Result

dRAS

# of Samples

# of Success

Result

102

9

0

False

10-6

22

22

True

103

55

16

False

10-2

26

5

False

106

22

22

True

10-1

9

0

False

  1. Property 4 specifies that the overexpression of HMGB1 will induce the expression of cell regulatory protein CyclinE.
  2. Property 5 specifies that the mutation of RAS will lead to the upregulation of CyclinD.