Figure 1

sRNA oxyS and its target s in the gene-regulation and protein-protein interaction networks. The dark green lines represent experimentally verified regulation and the dark yellow lines represent predicted regulation. The teal lines indicate indirect regulation (e.g., dinF downstream of lexA in the same operon). Yellow lines are also indirect regulation, but indicate genes of a predicted target. Dashed lines indicate regulated genes extended from an operon structure. Transcription factors under regulation of sRNA have pink borders. Arrow, T, and diamond heads represent positive, negative, and dual regulators, respectively. Circular heads represent predicted, thus unknown, regulation. OxyS regulation deals with multiple stress responses, such as oxidative and osmotic stresses.