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Table 2 Centrality measurements for the RNA targets in the transcription-regulatory interaction network

From: Modularity of Escherichia coli sRNA regulation revealed by sRNA-target and protein network analysis

 

All

Experimental

Experimental and predicted

 

Mean

Mean

Sim.

Mean

p-val

Mean

Sim.

mean

p-val

InD

2.3

3.3

2.3

0.013

2.7

2.3

0.024

OuD

2.3

5.8

2.6

0.13

2.9

2.5

0.32

Bet

6.6e-06

7.1e-5

7.8e-6

0.012

2.7e-5

7.6e-6

0.038

Clo

9.7e-02

8.2e-2

9.8e-2

0.55

8.4e-2

9.9e-2

0.66

Den

1.6e-03

8.9e-3

1.6e-3

0.036

2.3e-3

1.6e-3

0.13

IDR

N/A

1.8e-3

1.9e-40

0.023

6.3e-4

3.5e-4

0.15

I/T

 

42/65

110/240

  

Experimental & extended

Exp & pred & both extended

  

Mean

Sim.

mean

p-val

Mean

Sim.

mean

p-val

InD

 

3.2

2.3

5.0e-3

2.4

2.3

0.33

OuD

 

3.8

2.6

0.22

2.5

2.5

0.43

Bet

 

4.5e-05

7.7e-06

0.040

1.6e-05

7.7e-06

0.10

Clo

 

6.7e-02

9.9e-02

0.70

5.8e-02

9.9e-02

0.96

Den

 

6.1e-03

1.7e-03

0.071

1.4e-02

1.5e-03

0.020

IDR

 

3.8e-03

3.5e-04

0.037

1.8e-02

5.6e-04

0.0

I/T

 

66/92

251/450

  1. Those with significant values (p < 0.05) are indicated in boldface and those close to a p-value of 0.05 are underlined. The extended targets are targets located downstream of experimental or predicted sRNA targets in the same operons. InD: Indegree, OuD: Outdegree, Bet: Betweenness, Clo: Closeness, Den, Density, IDR: In-degree Ratio