Figure 1
From: Graphical models for inferring single molecule dynamics
Examples of types of commonly encountered biophysical time series data. (A) A time series for a molecule transitioning between a series of locally stable conformations. Such data often arise, for example, when studying protein domain movements or the dynamics of polymers tethered to a surface. (B) A time series for a molecule undergoing a stepping process. Such data often arise, for example, when studying proteins with unidirectional movements, e.g., helicases and motor proteins.