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Table 3 Low/not low model

From: An integrative method for scoring candidate genes from association studies: application to warfarin dosing

Gene Name P-Value
UBE3A E6AP ubiquitin-protein ligase 5.39E-05
VKORC1 Vitamin K1 2,3-epoxide reductase subunit 1 1.16E-04
SLA2 Src-like adapter protein 2 2.11E-03
DICER1 Dicer1, Dcr-1 homolog 3.76E-03
CYP2C9 cytochrome P450, family 2, subfamily C 5.49E-03
SLC22A1 solute carrier family 22 1.12E-02
BBC3 BCL2 binding component 3 1.49E-02
F8 Procoagulant component 1.74E-02
HMOX2 heme oxygenase (decycling) 2 1.79E-02
MUTED muted homolog 1.99E-02
VWF coagulation factor VIII VWF 2.40E-02
HSD3B7 3-beta-HSD VII 2.56E-02
SPIN1 spindlin 1 2.58E-02
SELPLG selectin P ligand 2.89E-02
FAM113B family with sequence similarity 113, member B 2.92E-02
F13B Fibrin-stabilizing factor B subunit 3.36E-02
MVP major vault protein 3.39E-02
UGT2B7 UDP glucuronosyltransferase 2B7 3.83E-02
AKR7A2 aflatoxin beta1 aldehyde reductase 4.17E-02
SERTAD1 CDK4-binding protein p34SEI 4.96E-02
  1. Top 20 genes with candidate gene-scores that significantly distinguish between low dose patients and non-low-dose patients (p≤0.05). P-Values are result of t test between low-dose and non-low-dose distributions of gene-scores. Genes in bold are significant after correcting for multiple hypothesis testing.