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Table 1 Simulated FDR and Power Rate (4 Analyses)

From: Sequential interim analyses of survival data in DNA microarray experiments

  Analysis
  1 2 3 4
  mean sd mean sd mean sd mean sd
#found genes 38 180 2422 896 4079 379 4232 290
FDR 0.051 0.158 0.028 0.006 0.027 0.003 0.027 0.003
APR 0.007 0.035 0.471 0.174 0.793 0.074 0.823 0.056
0.017 0.071 0.515 0.170 0.803 0.054 0.829 0.033
(S) 0.014 0.053 0.491 0.168 0.788 0.073 0.816 0.057
(L) 0.351 0.133 0.707 0.077 0.865 0.038 0.882 0.025
  1. The descriptive values for each interim analysis including the number detected genes, the simulated FDR, the real APR, and the APR estimates, all in the setting of τ = 50% altered genes and four interim analyses. These values correspond to Figure 4 (a) and Figure 5 (a).