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Table 1 Simulated FDR and Power Rate (4 Analyses)

From: Sequential interim analyses of survival data in DNA microarray experiments

 

Analysis

 

1

2

3

4

 

mean

sd

mean

sd

mean

sd

mean

sd

#found genes

38

180

2422

896

4079

379

4232

290

FDR

0.051

0.158

0.028

0.006

0.027

0.003

0.027

0.003

APR

0.007

0.035

0.471

0.174

0.793

0.074

0.823

0.056

0.017

0.071

0.515

0.170

0.803

0.054

0.829

0.033

(S)

0.014

0.053

0.491

0.168

0.788

0.073

0.816

0.057

(L)

0.351

0.133

0.707

0.077

0.865

0.038

0.882

0.025

  1. The descriptive values for each interim analysis including the number detected genes, the simulated FDR, the real APR, and the APR estimates, all in the setting of τ = 50% altered genes and four interim analyses. These values correspond to Figure 4 (a) and Figure 5 (a).
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BMC Bioinformatics

ISSN: 1471-2105

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