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Table 1 Ordered list of pathways with significant linear correlation between pathway metrics (either activity or consistency) and GI50.

From: The PathOlogist: an automated tool for pathway-centric analysis

Pathways

Rho

p value*

consistency: il2-mediated signaling events(NCI/Nature)

0.8049

2.18E-04

consistency: trk receptor signaling mediated by pi3k and plc-gamma(NCI/Nature)

0.791

4.91E-04

consistency: cadmium induces dna synthesis and proliferation in macrophages(Biocarta)

0.7511

3.71E-03

activity: toll-like receptor signaling pathway(Kegg)

0.7392

6.32E-03

activity: role of egf receptor transactivation by gpcrs in cardiac hypertrophy(Biocarta)

0.7042

2.60E-02

activity: agrin in postsynaptic differentiation(Biocarta)

0.694

3.80E-02

activity: downstream signaling in naïve cd8+ t cells(NCI/Nature)

0.6869

4.88E-02

  1. *after Bonferroni correction